Ontario Provincial Police (OPP) has reopened a portion of Highway 403 eastbound and westbound in Brantford following a police investigation.
In a tweet just after 1 p.m., OPP said the highway is closed between King George Road and Wayne Gretzky Parkway.
Brantford police said the incident involved a man in crisis.
Officials said just after 2 p.m. that the situation was resolved and the highway was reopen.