Seven people are facing charges and more arrests are expected following the largest seizure of fentanyl in the history of Waterloo Region.

Waterloo Regional Police say search warrants were executed Tuesday at homes on Selkirk Drive, Prosperity Street and Fairway Road North in Kitchener, and Rich Avenue in Cambridge.

Warrants were also executed at a hotel in Kitchener and a home in Durham.

At those six properties, officers allegedly found 1.5 kilograms of what is believed to be fentanyl. If it is fentanyl, police say, it would have a street value of about $450,000.

Also alleged to have been seized were 500 grams of crystal meth – with an estimated value of $40,000 – replica guns, prohibited weapons, two stolen vehicles, cash and other items.

On top of all that, police say they also seized six guns, some of which had been stolen in break-ins within Waterloo Region.

Seven people have been arrested in connection with the investigation on various charges related to drugs and weapons.

They include a 26-year-old Cambridge man, a 33-year-old Durham man, and five Kitchener residents – a 29-year-old woman, a 38-year-old man, a 46-year-old woman, a 32-year-old man and a 22-year-old woman.

Police say the arrests were the result of two separate investigations that coalesced into one as they learned more about the people they were looking into.

“Sometimes we don’t know the full picture until we get into these investigations and we actually start identifying who is involved,” Supt. Pat Dietrich said in an interview.

Police say investigators are still working the case and expect to make more arrests.