Police are appealing for help in the search for a Woodstock woman missing from her home. Brenda Duncan, 57, has been gone for over two and half days without anyone seeing or hearing from her.

Her husband David Duncan describes her as a conscientious woman who was dedicated to her family, work and faith.

He reported the disappearance and says this behaviour is very unlike her, "She was the first person to contact you if she was going to be tied up with something from work and late to be home."

Woodstock Police Service Chief Rod Freeman is as perplexed as her family. He says there is no reason for her sudden disappearance, she wasn't carrying much money and her credit cards and cell phone have not been used.

However, Freeman says that Duncan had called in sick for work around 8:00 a.m. just before disappearing on Tuesday, an indication she did not intend to go, though that's where her family believed she was headed.

An OPP helicopter has been conducting an aerial search of the area for any signs of Duncan and her red Mazda 5 with licence plate number BCSJ 791.

A bulletin has also been sent to police across Ontario and to the Canada Border Services Agency.

If anyone has information regarding her location they are encouraged to call Woodstock Police Service at 519-537-2323 or their local police department.