KITCHENER -- A woman has suffered life-threatening injuries after she was ejected from a car on Highway 403.

The Brant County OPP says they responded to the crash between Wayne Gretzky Parkway and Garden Avenue at around 5:52 p.m.

Police say that a driver was heading eastbound when the car crossed over the centre median, went airborne and collided with a westbound transport truck.

The car was reportedly cut in half, and the driver was thrown about 30 feet off of the highway.

The driver, a Hamilton woman who's about 20, was taken to a Hamilton hospital for her injuries.

The driver of the transport truck was taken to hospital for precautionary measures as well.

Debris from the crash also hit a third vehicle, but the driver of that car wasn't hurt.

Both westbound lanes were closed as a result of the crash. Police have not offered a reopening time, and the fire department has asked drivers to avoid the area.

It's not yet clear what caused the crash or whether any charges will be laid.

The highway is expected to reopen around 2 a.m.